SCORE SHEET FOR SCORING ENDPOINTS IN RODENTS PROJECT AUTHORISATION

0 SELECTED PEFA INDICATOR SCORES FOR UGANDA
(PROJECT TITLE) SCORE SHEET FOR SCORING ENDPOINTS EXPERIMENTAL TREATMENT
2003 SCOREBOARD 08192003 BEDFORD TIGER STADIUM TWINSBURG 130W 08232003

2006 PERCENTAGES AND COMPREHENSIVE ACT SCORES REPORTED BY ADE
2009 GRADES 38 MATHEMATICS RAW SCORE TO SCALE SCORE
2009 HARDAWAY INVITATIONAL RESULTS (TEAM INDIVIDUAL) TEAM SCORES NORTHVIEW

SCORE SHEET FOR SCORING ENDPOINTS IN RODENTS


SCORE SHEET FOR SCORING ENDPOINTS IN RODENTS


Project Authorisation number and Group:


Date: Time: Personal Authorisation Number:


Name of person scoring:


Name of PI: Contact Tel No: After Hours:


Indicators

Scoring of independent variables:

Score of each animal in group

Animal








General Health

Eating





Locomotion





Behaviour:


  1. drinking and eating well

  2. change in eating or drinking habit

  3. inappetance.

  4. not eating/drinking, severely dehydrated


  1. walking normally

  2. limping, stiffness

  3. swollen limbs

  4. severely restricted mobility


  1. normal

  2. away from littermates

  3. aggressive or huddled in corner

  4. severe distress








Appearance


0. Normal

1. ruffled fur

2. animal appears depressed , hunched, reluctant to move

3. animal appears severely depressed.








Weight loss





  1. normal

  2. 5 – 10%

  3. 10-19%

  4. >20%








End point


If 10% body weight loss, neurological impairment of hindlimb prevents feeding and drinking- contact user/cull







Operation site

Wound



  1. Healed

  2. Open slightly but dry

  3. Signs of infection wet

  4. Gaping and open wound with pus







Bleeding


  1. Signs of blood coagulated

  2. Small amount of bleeding from wound

  3. Continuous drip of blood

  4. Copious bleeding







Sutures/clip

  1. Slightly loose

  2. Becoming detached and wound opening

  3. Nearly detached and wound open

  4. Completely detached and wound gaping







POST OPERATIVE SUPPORT

Analgesic administration

0.Animal relaxed appears pain free

1. Animal showing signs of mild discomfort

2. Animal agitated showing signs of moderate discomfort

3. Animal in severe discomfort







Drug








Dose








Fluids by SC injection








Other drugs








Total Score








For Total Scores

0 = normal: no action *** A score of 3 in any one category: euthanase / Schedule 1 kill

1-4 = moderate changes: should be monitored daily

5-10 = significant changes: monitor twice daily

>10 = euthanase


Signature of person scoring:



REFERENCES

1. Morton, D.B. (1997). A scheme for the recognition and assessment of adverseeffects. In:Animal Alternatives, Welfare and Ethics. (Eds. LFM vanZutphen and M. Balls). ElsevierScience, Amsterdam. pp. 235-241.

2. Morton, D.B. (1998). The use of score sheets in the implementation of humaneend points.Proceedings of the Joint ANZCCART / NAEAC Conference on EthicalApproaches to Animalbased Science (Eds. D. Mellor, M. Fisher and G.Sutherland), ANZCCART, Adelaide andWellington. pp: 75-82.



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