SECTION ON NEPHROLOGY URINALYSIS THE ROUTINE URINALYSIS REMAINS AN

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Hypertension in Pediatrics: How to diagnose, evaluate and initiate treatment

Section on Nephrology

Urinalysis


The routine urinalysis remains an important tool in diagnosing children with renal disease. However, over the years the usefulness of the test as a routine screening procedure as part of health maintenance has been called into question. This stems largely from the large number of false positive tests that may require expensive and invasive testing to determine the true health of an individual. On the other hand, many pediatricians continue to perform a urinalysis as part of an annual or biannual well child visit. The urinalysis is still an important tool in diagnosing renal disease in acutely ill children and certain groups of children such as those with a family history of renal disease, obesity, hypertension, and diabetes mellitus.


The interpretation and further evaluation of children with abnormal results from a urinalysis remains an area that many pediatricians feel they would like more and ongoing education. A session devoted to the interpretation of an abnormal urinalysis, especially as it relates to the presence of increased amounts of blood and protein, has been offered at the NCE annually has been consistently attended by over 200 attendees every year. In an informal survey among pediatric nephrologists this is a topic commonly asked for in local CME activities and an abnormal urinalysis in an otherwise healthy child is a common reason for referral. Further, with limited health care resources these days, educating primary care physicians on the appropriate groups and times to perform a urinalysis to reduce long-term healthcare costs is another important goal of this CME activity. For these reasons, when to perform a urinalysis, in whom to do it, and the initial evaluation when it is abnormal remains an important CME topic for the AAP membership.


Patel, HP. The abnormal urinalysis. Pediat Clinics of NA 2006;53:325-337



Fluid Management in dehydrated children in the office and acute care center


Fluid management has always been an important topic for pediatricians as children, especially infants, are at increased risk for dehydration. The management of the dehydrated child is constantly being refined from the ground breaking work of Segar and Holliday in the 1950 and 1960’s. New therapies for the outpatient management children previously hospitalized, such as oral rehydration therapy and IV bolus therapy, has revolutionized the care. On the other hand, complications of inappropriate fluid have increased in importance, such as hyponatremia.


Fluid therapy, especially that which can be delivered in the office or acute care center, and common electrolyte abnormalities and their management have been popular CME topics every year at the NCE. These sessions are consistently well attended indicating their importance to practicing pediatricians.




Holliday, MA, Friedman, AL, Segar, WE, et al. Acute hospital-induced hyponatremia in children: a physiologic approach. J Pediatr 2004; 145:584.


Moritz, ML, Ayus, JC. Prevention of hospital-acquired hyponatremia: a case for using isotonic saline. Pediatrics 2003; 111:227


Fontaine O. Garner P. Bhan MK. Oral rehydration therapy: the simple solution for saving lives. BMJ. 334 Suppl 1:s14, 2007 Jan 6.


Urinary Tract Infections in Children


Urinary tract infections remain an important problem in pediatrics. They are the third most common site for infection in children, especially in females infants and toddlers, following behind upper and lower respiratory infections. Approximate 8% of febrile female and uncircumcised male infants under the age of 2 years have a UTI. Renal scarring can result if a UTI is unrecognized or perhaps if treatment is significantly delayed. Progressive renal scarring can then lead to long-term consequences such as hypertension, chronic renal failure, and complications during pregnancy when affected children become adults.


A session on the evaluation and management of a child with a UTI has been offered biannually at the NCE and has been consistently attended by over 200 hundred attendees. New information and procedures has also been generated over the years changing the management and evaluation for such child. Several international multicenter studies have consistently shown that medical management with prophylactic antibiotics and active surveillance for infection in children with vesicoureteral reflux leads to an equivalent long term outcome as surgical reimplantation of the refluxing ureter. The Deflux procedure, which can correct reflux cystoscopically and is now widely performed by pediatric urologists, may change our approach to the child with a UTI and reflux. The role of prophylactic antibiotics in the management of children with reflux has also been questioned recently and is the subject of a new multicenter NIH study. New imaging modalities have evolved over the years and their place in the evaluation of the child with a UTI remains a source of controversy and evolution.


Because of the frequency and complexity of the management of children with UTIs, the evolution of new information, and the fact that the responsibility for the care of most children with this problem is in the hands of the primary care physician, the evaluation and management of children with UTIs remains an important CME topic for the AAP membership.


Downs, SM. Technical report: urinary tract infections in febrile infants and young children. The Urinary Tract Subcommittee of the American Academy of Pediatrics Committee on Quality Improvement. Pediatrics 1999;103:e54

Hypertension in Pediatrics: How to diagnose, evaluate and initiate treatment

The prevalence of elevated blood pressure in children and adolescents is increasing due to the obesity epidemic – recent screening studies have shown that over 10% of children with BMI ≥95th percentile have persistently elevated BP. Many of these children are also at risk for type 2 diabetes and hyperlipidemia and may have other risk factors for cardiovascular disease such as a family history of hypertension. Pediatricians therefore need to be able to understand how to correctly diagnose hypertension, how to screen for the possibility of underlying kidney or heart disease that may be causing the high BP, and when referral to a specialist for further evaluation is indicated. In addition, the increasing numbers of hypertensive children and adolescents also make it important for pediatricians to understand the role of non-pharmacologic and pharmacologic approaches to the treatment of hypertension, and when it is appropriate for such treatment to be initiated in the primary care setting. Finally, a thorough understanding of the approach to hypertension in childhood and adolescence is consistent with the pediatrician’s important role in disease prevention – specifically, the prevention of future cardiovascular disease.

Reference:

National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 114:555-576, 2004.


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