IVF USING DONOR OOCYTES PATIENT INFORMATION LEAFLET 1 CONTACT

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IVF USING DONOR OOCYTES PATIENT INFORMATION LEAFLET 1 CONTACT




IVF USING DONOR OOCYTES

IVF USING DONOR OOCYTES PATIENT INFORMATION LEAFLET 1 CONTACT

Patient information leaflet


1 CONTACT NUMBERS 2

2 OPENING HOURS 2

3 BACKGROUND 3

4 DONORS (THOSE WOMEN DONATING EGGS) 3

4.1 Matching 3

5 COUNSELLING 3

6 HFEA REGISTER 4

7 WELFARE OF THE CHILD 4

8 RECIPIENTS (THOSE WOMEN RECEIVING DONATED EGGS) 4

9 IN VITRO FERTILISATION (IVF) WITH DONOR EGGS AND PARTNER’S SPERM 5

10 RESULTS 5

11 WILL THE PREGNANCY BE NORMAL? 5

12 OUTCOME 5

13 FINANCE 6

14 COMPLAINTS 6


IVF USING DONOR OOCYTES



1CONTACT NUMBERS


Ward 35 01382 633835 (voicemail outwith 8.00 am – 5 pm)


Anne McConnell 01382 632111 (voicemail outwith 8.00 am – 5.30 pm)

Email [email protected]


Appointments secretaries 01382 496475 (8.45 am – 4.45 pm)




Emergency calls for medical staff outwith 8.00 am – 5 pm:


Mobile ‘phone 07774 694765. If there is no reply from this number, you should contact the hospital switchboard (01382 660111) who will contact one of the consultant staff for you.


2OPENING HOURS


The Unit is open;




DONOR OOCYTE IVF

3BACKGROUND

Primary or premature ovarian failure has been estimated to occur in approximately 1% of women. For such women their only hope of a pregnancy lies in the use of eggs donated by a healthy female volunteer. The same technique may also apply to women whose ovaries have been removed or where she is at risk of passing on some genetic disorder by her own eggs and may also be advised for couples with repeated failed IVF cycles.


4DONORS (THOSE WOMEN DONATING EGGS)

Healthy female volunteers aged 35 years or less may donate following careful counselling. Some of these volunteers approach the Unit directly wishing to donate eggs, while others after further discussion agree to take part in an egg sharing programme.


All donors give a full medical and family history, followed by screening for certain transmittable diseases including Hepatitis B and C, HIV, syphilis and gonorrhoea prior to being accepted on to the programme. It is emphasised that this is not a guarantee that the patient is free of disease, which could in theory only become apparent after the screening process. The risk of this is very small indeed. The physical characteristics of the donors are recorded.


The donors undertake to use certain drugs including a series of injections to ensure the development of more than one egg. This is called ‘stimulation’ and is identical to the treatment given to IVF patients. The treatment cycle is monitored by ultrasound scans to check the growth of follicles. When the follicles are of the correct size, a final injection of a hormone, hCG, is given to mature the eggs. Egg collection in theatre oocurs approximately 36 hours after this injection.


4.1Matching

As far as possible we try to match the general characteristics, eg height, hair and eye colour. Often exact matching is not possible because of a shortage of donors. However it is a fact that there is a very great variation in the characteristics of children even when both partners are the natural parents. We would not use a donation from a person of another race.


5COUNSELLING

It is recognised that having treatment can be a stressful and challenging process. Anne Chien, our independent counsellor, is available to give you the time and space to explore your thoughts and feelings around your treatment.


Implications counselling will be organised for patients who are considering treatment which involves either donating (including sharing) or using donated eggs, sperm or embryos and also for those considering surrogacy. Implications counselling enables you to consider your thoughts and feelings about the complex emotional, practical and ethical issues around such treatment in a supportive way. You will be encouraged to consider how you might manage the information around donation or surrogacy and how that might impact on yourselves, any child born as a result and on others involved in your treatment. Each counselling session lasts around an hour and your counsellor can help you to decide about further appointments. This counselling is not an assessment, it is to help you make a fully informed decision about your treatment.


6HFEA REGISTER

The Human Fertilisation and Embryology Authority (HFEA) keeps a confidential register of information about donors, patients and treatments. This register was set up on 1st August 1991 and therefore contains information concerning children conceived from licensed treatments from that date onwards.


Until April 2005, donors could choose to remain anonymous and, although they had to give identifying details for the HFEA register, these remained confidential. However, on 1st April 2005, the law changed to allow people conceived through donation to find out who the donor was, once they reach the age of 18. Further changes to the HFE Act apply from 1st October 2009 which mean that donor-conceived people over 16 years of age will be able to access anonymous information about their donor and find out whether they have any genetically related donor conceived siblings. They will also be able to make contact with genetically related donor-conceived siblings (provided both parties consent).


At your request, we can provide you with non-identifying information about donors.



7WELFARE OF THE CHILD

The Human Fertilisation and Embryology Act of 1990 requires that the welfare of the child (or any existing children) must be taken into account before treatment can start. (A separate leaflet covering the HFEA statement on this is included).


8RECIPIENTS (THOSE WOMEN RECEIVING DONATED EGGS)

Most women with ovarian failure will already be taking hormone replacement tablets. Prior to treatment starting, these will be stopped and you will be started on tablets called Progynova and the dose will be increased until the lining of your womb is thick enough to receive the embryos. We may carry out a ‘dummy’ cycle one to two months before your treatment, to ensure that the lining of the womb can be thickened sufficiently; this will allow us to know the correct dose of drugs to use. Your cycle will be monitored by ultrasound scans, to bring you into line with the donor’s cycle. You will also be given a supply of Cyclogest pessaries. You will continue to take these tablets and pessaries until a pregnancy test confirms whether or not you are pregnant. If you do become pregnant, you would need to take hormone treatment by suppositories and tablets for the first four months of your pregnancy.


9IN VITRO FERTILISATION (IVF) WITH DONOR EGGS AND PARTNER’S SPERM

The eggs will be collected and then fertilised with the partner’s sperm in the laboratory (IVF). The fertilised eggs (embryos) are replaced in the womb of the recipient by embryo transfer, normally five days after the eggs are collected, although sometimes after three days. The maximum number of embryos transferred is two but we encourage the transfer of a single embryo.


10RESULTS

Results for the year ending 31st December 2016 show a live birth rate of 26% (5/18) and the continuing pregnancy rate for the year ending 31st December 2017 is 73% per treatment cycle started (11/15).


11WILL THE PREGNANCY BE NORMAL?

The risks of a child from IVF using donated eggs being born with a congenital problem or handicap are exactly the same as for any other IVF pregnancy. There are no special risks to the baby and we would advise routine antenatal care for any such pregnancy. This would normally include an offer of antenatal screening and the risks of an unexpected birth abnormality are small.


There is now some evidence that women who have been treated with donated eggs (or sperm or embryos) have a greater chance of blood pressure problems in pregnancy. About 1 in 10 first time mothers will have a particular complication of pregnancy called pre-eclampsia. In most of these cases, there will be no long term effects on either the mother or baby but intervention such as induction of labour is more common. If a blood pressure problem is neglected or rarely where it becomes severe, there can be serious risks to the mother or baby. Antenatal care is designed to detect these problems early in their development and fortunately they remain rare.


12OUTCOME

It is very important that you keep in touch with us regarding the outcome of your pregnancy because we have a legal obligation to notify the Human Fertilisation and Embryology Authority.


13FINANCE

Your treatment may be funded by your health board but if this is not the case, then you will need to self-fund. The current cost of a treatment cycle is included in the separate leaflet on costs.


14COMPLAINTS

If you feel that there is any area for complaint regarding your treatment, there are various ways to deal with this;


  1. Contact Anne McConnell at the Assisted Conception Unit.

  2. Contact the Consultant in charge of your care.

  3. The Trust also has its own complaints procedure which you may wish to use. The normal

process would be for patients to write to the Chief Executive of the Trust; however, any correspondence may be read by other members of his staff or those working in the Patient Liaison Service, therefore you must bear in mind that, although the normal rules of confidentiality would apply, the special protection offered by the Human Fertilisation and Embryology Act for patients undergoing assisted conception treatment would not be followed. You may therefore wish to address any letters of complaint to either of the following, c/o the Assisted Conception Unit, Ward 35;



The above are both named on our licence held by the Human Fertilisation and Embryology Authority.

M Rajkhowa/E Lowe, March 2007


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