ALISRA UNIVERSITY COURSE SYLLABUS PHARMACEUTICAL ORGANIC CHEMISTRY PRACTICAL COURSE

ALISRA UNIVERSITY COURSE SYLLABUS PHARMACEUTICAL ORGANIC CHEMISTRY PRACTICAL COURSE




Al-isra University

Course Syllabus

Pharmaceutical Organic Chemistry Practical



Course No.

Credit hours

Pre- or Co- requested

Year (semester)

Lec./lab. Time

501257

1

Organic chemistry 501256

2012-2013 (2)

11-2 Sun, Mon,

1-4 The



Lecturer Name

Ranke

Room No.

Tel No.

E-mail

Office Hours

Rami Njadat

Instructor

330

2685

[email protected]

10-11 daily



Course Description:

This lab is divided into many parts: The first part include various separation and purification techniques of organic compounds that an organic chemist uses daily; including crystallization, distillation and extraction and organic qualitative analysis. The second part deals with the synthesis of certain organic compounds of pharmaceutical importance.

Course Objective:

The objectives of this course are:

  1. Familiarize students with techniques commonly used in the organic laboratory.

  2. Understand how to determin the solubility and functional group classification test.

  3. Learn how to chemically synthesis new compound.



Intended Learning Outcomes:

Successful completion of this course should lead to the following learning outcomes:

  1. Knowledge and understanding: the student should

  1. Learn various separation techniques including Recrystallization, Extraction.

  2. Learn physical and chemical characteristics of organic compounds including determination of the solubility.

  3. Learn various identification techniques including melting point determination.



  1. Professional skills

  1. To follow general policies and safety precautions in the lab

  2. Proper handling of glassware and dealing with heat source in the lab.

  3. Different lab techniques as filtration, distillation and drying.



  1. Transferable skills

  1. Adapt group discussion and learn how to respect other opinion.

  2. Learn the principle of team-work.

Reading List:

Text Book

Organic Chemistry: A Short Course By Harold Hart, Leslie E. Carine, David J. Hart. Publisher: Houghton Mifflin College; 10th edition ( January 1999) ISBN. 0395902258

Other References

Louis F.Fieser and Kenneth L Williamson, organic experiment 1987.



Grade Distribution:

Assessment

Grade

Quizzes

10%

Midterm Exam

25%

Reports

15%

Evaluation

10%

Final Examination

40%



Week

Topic detailes

Assessment

1.

General instruction and safety rules


2.

Melting point


3.

Boiling point and distillation


4.

Recrystallization


5.

Extraction


6.

Steam distillation


7.

Thin layer chromatogrphy

Midterm exam

8.

Organic qualitative analysis


9.

Synthesis of paracetamol


10.

Synthesis of dibenzlactone


11.

Heterocyclic synthesis of 2-methylbenzimidazol


12.

Revision


13.

Final examination week

Final examination



Teaching and learning strategies:

1. Tutorial and laboratory sessions

2. E-learning for assignment and homeworks

3. Class room discussion.





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